Itraconazole 100mg capsules
Itraconazole 100mg is an antifungal medicine. It is used to treat certain kinds of fungal or yeast infections.
Rare cases of serious hepatotoxicity have been observed with SPORANOX treatment, including some cases within the first week. It is recommended that liver function monitoring be considered in all patients receiving SPORANOX. Treatment should be stopped immediately and liver function testing should be conducted in patients who develop signs and symptoms suggestive of liver dysfunction.
If neuropathy occurs that may be attributable to SPORANOX® Capsules, the treatment should be discontinued.
If a cystic fibrosis patient does not respond to SPORANOX Capsules, consideration should be given to switching to alternative therapy. For more information concerning the use of itraconazole in cystic fibrosis patients see the prescribing information for SPORANOX Oral Solution.
Transient or permanent hearing loss has been reported in patients receiving treatment with itraconazole. Several of these reports included concurrent administration of quinidine which is contraindicated (see BOXED WARNING: Drug Interactions, CONTRAINDICATIONS: Drug Interactions and PRECAUTIONS: Drug Interactions). The hearing loss usually resolves when treatment is stopped, but can persist in some patients.
Never take SPORANOX if you:
• have had heart failure, including congestive heart failure.
• are taking any of the medicines listed below. Dangerous or even life-threatening abnormal heartbeats could result:
• quinidine (such as Cardioquin, Quinaglute, Quinidex).
• dofetilide (such as Tikosyn™).
• cisapride (such as Propulsid).
• pimozide (such as Orap).
• levacetylmethadol (such as Orlaam).