When you must not take Oxycontin Oxycodone ER (generic)
Oxycontin Oxycodone ER (generic) OXYCODONE is a pain reliever. It is used to treat constant pain that lasts for more than a few days.
Do not take OXYCONTIN tablets if you:
• suffer from shallow breathing or have any breathing problems such as acute asthma, chronic bronchitis or impaired lung function
• are severely drowsy or have a reduced level of consciousness.
• suffer from irregular or fast heartbeats or changes in the way the heart beats.
• have heart problems or heart disease including if due to long term lung disease.
• have just drunk a large amount of alcohol, regularly drink large amounts of alcohol or have confusion and shaking due to. stopping drinking alcohol
• suffer from convulsions, fits or seizures.
• have a head injury, a brain tumour or have raised pressure within the head, brain or spinal cord.
Do not take this medicine after the expiry date (EXP) printed on the pack.
If you take it after the expiry date has passed, it may not work very well.
Do not take it if the packaging is torn or shows signs of tampering. Do not take this medicine if you are pregnant or intend to become pregnant whilst taking this medicine.
Common Adverse Reactions (>5%)
Adverse OXYCONTIN Placebo
Reaction (n=227) (n=45)
Constipation (23) (7)
Nausea (23) (11)
Somnolence (23) (4)
Dizziness (13) (9)
Pruritus (13) (2)
Vomiting (12) (7)
Headache (7) (7)
Dry Mouth (6) (2)
Asthenia (6) –
Sweating (5) (2)
Oxycodone may produce release of histamine with or without associated peripheral vasodilation. Manifestations of histamine release and/or peripheral vasodilation may include pruritus, flushing, red eyes, sweating, and/or orthostatic hypotension.
Oxycodone and its metabolites are excreted primarily via the kidney. The amounts measured in the urine have been reported as follows: free oxycodone up to 19%; conjugated oxycodone up to 50%; free oxymorphone 0%; conjugated oxymorphone ≤ 14%; both free and conjugated noroxycodone have been found in the urine but not quantified. The total plasma clearance was 0.8 L/min for adults.